Table 3.

Body fat distribution measures and breast cancer risk

	Pre-menopausal					Post-menopausal
	Cases/Controls	OR1	95% CI	OR2	95% CI	Cases/Controls	OR1	95% CI	OR2	95% CI
Waist to hip ratio
≤0.82	123/144	Ref		Ref		65/93	Ref		Ref
0.83–0.87	128/120	1.14	0.79–1.65	1.20	0.82–1.74	146/117	1.58	1.03–2.40	1.59	1.04–2.42
0.88–0.92	105/121	0.98	0.66–1.44	1.07	0.72–1.60	120/116	1.22	0.79–1.88	1.24	0.80–1.92
>0.92	104/93	1.19	0.80–1.79	1.38	0.89–2.12	169/144	1.43	0.95–2.18	1.48	0.97–2.26
p for trend			0.55		0.22			0.33		0.27
Waist circumference (cm)
≤87.88	137/143	Ref		Ref		87/94	Ref		Ref
87.89–97.75	124/119	1.02	0.70–1.46	1.26	0.85–1.88	119/118	1.07	0.71–1.61	1.13	0.73–1.76
97.76–110.25	107/116	0.93	0.64–1.37	1.47	0.88–2.44	154/121	1.35	0.90–2.02	1.51	0.92–2.48
>110.25	92/100	0.98	0.65–1.48	2.25	1.07–4.74	140/137	1.00	0.67–1.50	1.23	0.64–2.34
p for trend			0.84		0.04			0.96		0.48
Per 5 cm		0.99	0.95–1.03	1.10	1.00–1.22		1.00	0.96–1.04	1.03	0.94–1.13
Hip circumference (cm)
≤103.18	127/138	Ref		Ref		107/99	Ref		Ref
103.19–111.63	133/111	1.25	0.86–1.81	1.60	1.07–2.39	129/126	0.99	0.67–1.47	0.99	0.65–1.51
111.64–123.15	101/116	1.00	0.68–1.46	1.60	0.98–2.60	145/122	1.16	0.79–1.72	1.16	0.71–1.89
>123.15	100/113	1.07	0.72–1.59	2.91	1.39–6.10	119/123	0.88	0.59–1.31	0.87	0.45–1.71
p for trend			0.99		0.01			0.54		0.69
Per 5 cm		0.98	0.93–1.03	1.12	0.99–1.27		0.98	0.94–1.03	0.97	0.87–1.08

OR1: Adjusted for age, ethnicity, country of origin (United States, Caribbean, other), education, family history of breast cancer, history of benign breast disease, age at menarche, age at menopause (for postmenopausal women), parity (continuous), breastfeeding (yes/no), age at first birth, HRT use (ever/never), OC use (ever/never). OR2: Further adjusted for BMI.