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. 2013 Nov 20;2013:391021. doi: 10.1155/2013/391021

Table 1.

Local tumor control following SBRT for early stage NSCLC.

References No. of fractions No. of patients/no. of total patients Fractional dose (isocenter, Gy) Median followup (months) Local control Dose calculation algorithm
Kopek et al. [17] 3 62/88 15.0 44.0 93.1% PB
Koto et al. [22] 20/31 15.0 32.0 75.0% Batho
Hoyer et al. [24] 40/40 15.0 29.0 92.5% NSS
Bral et al. [35] 23/40 18.0 16.0 91.3% NSS, BrainLab
Ricardi et al. [26] 62/62 18.8 28.0 93.6% CC
Guckenberger et al. [37] 32/124 19.2 14.0 100.0% CC
Ng et al. [30] 12/20 20.0 21.0 83.3% NSS, BrainLab
Andratschke et al. [31] 92/92 20.8* 21.0 89.1% NSS
Nyman et al. [18] 45/45 21.0 43.0 80.0% Batho
Vahdat et al. [19] 20/20 21.3* 43.0 95.0% NSS, Cyberknife
Crabtree et al. [33] 76/76 21.8 19.0 93.4% NSS, Triology
Baumann et al. [20] 57/57 22.0 35.0 93.0% PB
Timmerman et al. [21] 59/59 22.5 34.4 98.2% NSS
Turzer et al. [38] 31/36 22.9 13.8 100.0% CC
Fakiris et al. [16] 34/70 25.0 50.2 97.1% NSS
van der Voort van Zyp et al. [36] 59/70 25.8 15.0 96.6% NSS, Cyberknife
Matsuo et al. [23] 4 101/101 12 31.4 86.1% PB
Baba et al. [28] 85/124 12 26.0 87.1% NSS
Stephans et al. [32] 5 56/86 10.2 19.8 96.4% NSS, BrainLab
Takeda et al. [29] 63/63 12.5 24.0 95.6% SC
Lagerwaard et al. [25] >100/— 15.0 29.0 95.7% NSS, BrainLab
Onimaru et al. [34] 8 to 10 17/45 6.0 18.0 70.6% PB & SC
Onishi et al. [39] 35/35 7.3 13.0 94.3% NSS
Xia et al. [27] 43/43 10.0 27.0 96.0% NSS, Gamma knife

 *Median or mean dose; Personal communication with Dr. Lagerwaard.  Image guidance applied. CC: Collapsed cone; NSS: not specifically stated; PB: pencil beam; S: superposition.