Table 3.
Proportion of women in which non-Lactobacillus species were detected
| |
Nugent I (0–3) |
Nugent II (4–6) |
Nugent III (7–10) |
p-values for trend |
||||
|---|---|---|---|---|---|---|---|---|
|
N = 73 |
N = 25 |
N3 = 79 |
||||||
| |
Qualitative1 detection |
Quantitative2 detection |
Qualitative1 detection |
Quantitative2 detection |
Qualitative1 detection |
Quantitative2 detection |
Qualitative detection |
Quantitative detection |
| N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | p-value | p-value | |
|
A. vaginae |
55 (75) |
6 (8) |
22 (88) |
13 (52) |
79 (100) |
75 (95) |
<0.0001 |
<0.0001 |
|
S. sanguinegens |
10 (14) |
2 (3) |
9 (36) |
5 (20) |
59 (75) |
53 (67) |
<0.0001 |
<0.0001 |
|
L. amnionii |
30 (41) |
2 (3) |
15 (60) |
6 (24) |
68 (86) |
63 (80) |
<0.0001 |
<0.0001 |
| BVAB 1 |
23 (31) |
5 (7) |
11 (44) |
6 (24) |
53 (67) |
43(54) |
<0.0001 |
<0.0001 |
| BVAB 2 |
15 (21) |
2 (3) |
10 (40) |
8 (32) |
72 (91) |
69 (87) |
<0.0001 |
<0.0001 |
| BVAB 3 |
10 (14) |
6 (8) |
11 (44) |
9 (36) |
52 (66) |
52 (66) |
<0.0001 |
<0.0001 |
| BVAB-TM7 |
0 (0) |
0 (0) |
6 (24) |
6 (24) |
27 (34) |
27 (34) |
<0.0001 |
<0.0001 |
|
Megasphaera type 1 |
30 (41) |
1 (1) |
17 (68) |
9 (36) |
68 (86) |
64 (81) |
<0.0001 |
<0.0001 |
|
Megasphaera type 2 |
5 (7) |
0 (0) |
3 (12) |
2 (8) |
25 (32) |
22 (28) |
<0.0001 |
<0.0001 |
|
Eggerthella-like bacterium |
47 (64) |
3 (4) |
18 (72) |
6 (24) |
75 (95) |
62 (78) |
<0.0001 |
<0.0001 |
|
M. curtisii |
1 (1) |
1 (1) |
3 (12) |
3 (12) |
20 (25) |
20 (25) |
<0.0001 |
<0.0001 |
|
M. mulieris |
5 (7) |
1 (1) |
4 (16) |
3 (12) |
16 (20) |
12 (15) |
0.018 |
0.003 |
|
G. vaginalis |
71 (97) |
6 (8) |
24 (96) |
10 (40) |
79 (100) |
69 (87) |
0.19 |
<0.0001 |
|
M. hominis |
11 (15) |
3 (4) |
7 (28) |
4 (16) |
50 (63) |
46 (58) |
<0.0001 |
<0.0001 |
|
U. parvum |
37 (51) |
18 (25) |
10 (40) |
5 (20) |
40 (51) |
22 (28) |
0.99 |
0.64 |
|
U. urealyticum |
7 (10) |
4 (5) |
4 (16) |
2 (8) |
14 (18) |
11 (14) |
0.15 |
0.08 |
|
F. magna |
30 (41) |
30 (41) |
17 (68) |
17 (68) |
50 (63) |
50 (63) |
0.006 |
0.006 |
| Prevotella spp. | 70 (96) | 3 (4) | 24 (96) | 12 (48) | 77 (97) | 75 (95) | 0.59 | <0.0001 |
1Presence versus absence as determined by the target qPCR.
2Presence (≥ cut-off/ml) versus absence (< cut-off/ml) with cut-off determined by ROC curve analysis.
3 N indicates number of participants.