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. 2013 Oct 8;11:251. doi: 10.1186/1479-5876-11-251

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Copyright © 2013 Zhou et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Notch1 signaling improves cardiac function in isolated rat hearts. A-D, Measurement of heart rate (HR), left ventricular developed pressure (LVDP) and maximal (dP/dt_max) and minimal (dP/dt_min) value of the first derivative of left ventricular pressure. Data were shown as the percentage of the values recorded at 1 min before ischemia. Data were presented as mean±SD, n=6. a: I/R+N1ICD vs I/R; P<0.05; b: IPC vs I/R, P<0.05; c: IPC vs IPC+shRNA, P<0.05; d: IPost vs I/R, P<0.05; e: IPost vs IPost+shRNA, P<0.05.