Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CRY1 mutations that mimic phosphorylation of Ser-588 cause lengthened circadian periods when used to rescue rhythms in Cry1−/−/Cry2−/− cells. A–E, traces show Per2-luc reporter rhythms (base line-subtracted) from cells transfected with WT or mutant CRY1 as noted in the legends. F shows quantitation of the period lengths from WT, S588A, and S588D rescues such as those shown in E. (n = 8, ***p < 0.001).
