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Specific activities of P-protein variants at different redox conditions relative to the wild-type protein. The columns show mean activities of recombinant P-protein ± S.D. (error bars) (n = 4) preincubated with 1 mm (black) or zero (gray) dithiothreitol in the glycine-bicarbonate exchange reaction. The numbers indicate percentage activities relative to the corresponding wild-type control. The number in parentheses shows the percentage relative to fully activated wild-type P-protein.
