. 2013 Oct 16;288(49):35346–35357. doi: 10.1074/jbc.M113.507525

TABLE 3.

mRNA for PI3K isoforms in RAW264.7 and RAW264.7-derived osteoclasts

Quantitative PCR analysis of PI3K isoforms in RAW264.7 cells and after differentiation into osteoclast-like cells. Differentiation of osteoclasts with RANKL was accompanied by increase in expression of message for PI3Kβ and decrease in PI3Kγ. Values are mean ± S.E. from four independent experiments. Student's t test was used for statistical analyses.

	Without RANKL	With RANKL
Pik3ca, p110-α	0.0029 ± 0.0007	0.0032 ± 0.0006
Pik3cb, p110-β	0.0109 ± 0.0023	0.0223 ± 0.0035^a
Pik3cg, p110-γ	0.0065 ± 0.0010	0.0022 ± 0.0007^a
Pik3cd, p110-δ	0.0027 ± 0.0001	0.0016 ± 0.0002

^a p < 0.05 for the effect of RANKL.