TABLE 2.

Summary of results obtained with mouse decorin and its mutants

Protein	Location of mutated residue(s)	Oligomeric statea	Collagen bindingb
WT		Monomer-dimer equilibrium	Yes
Y51A/R52A/Q54A	N-terminal cap	Monomer-dimer equilibrium	Yes
Q61N	LRR1	Monomer	No
Y130N	LRR4	Monomer	No
R151E	LRR5	Monomer-dimer equilibrium	No

^a Determined by SEC-MALS (Fig. 2) and analytical ultracentrifugation (Figs. 3 and 4).

^b Determined by inhibition of collagen fibrillogenesis and solid-phase binding (Fig. 6).