. 2013 Nov 20;2013:736856. doi: 10.1155/2013/736856

Table 2.

Biomarkers associated with lipids, oxidative stress, and inflammation in serum.

Group	Dose (mg/kg body weight/day)	Triglycerides (mg/dL)	Total cholesterol (mg/dL)	NEFA (mEq/L)	HDL-C (mg/dL)	LDL/VLDL-C (mg/dL)
m/m	—	114 ± 9^c	110 ± 8^c	0.62 ± 0.02^c	51.01 ± 3.55^c	522 ± 4^b
db/db
Veh	—	263 ± 21	186 ± 8	2.55 ± 0.06	80.95 ± 2.49	570 ± 17
GS	20	198 ± 16^a	179 ± 14	1.98 ± 0.04^c	90.88 ± 7.68	394 ± 21^a
GS	100	175 ± 8^b	163 ± 11	1.56 ± 0.15^c	95.88 ± 3.16^b	355 ± 13^c

Group	Dose (mg/kg body weight/day)	ROS (fluorescence/min/mL)	TBARS (nmol/mL)	Adiponectin (ng/mL)	Resistin (pg/mL)	TNF-α (pg/mL)	IL-6 (pg/mL)

m/m	—	790 ± 175^a	18.33 ± 0.46^c	6.32 ± 0.27^c	522 ± 4^b	117 ± 17^a	11.08 ± 0.33^c
db/db
Veh	—	1,563 ± 144	22.48 ± 0.51	3.18 ± 0.09	570 ± 17	261 ± 28	21.27 ± 2.07
GS	20	950 ± 112^a	11.88 ± 1.45	3.68 ± 0.12^b	394 ± 21^c	162 ± 30^a	14.90 ± 2.07
GS	100	840 ± 70^b	9.06 ± 1.19^c	4.63 ± 0.19^c	355 ± 13^c	133 ± 13^b	12.45 ± 1.19^b

m/m, Misty; Veh, vehicle-treated db/db mice; GS20, GS20 mg/kg body weight-treated db/db mice; GS100, GS100 mg/kg body weight-treated db/db mice. The results are presented as the means ± S.E.M. ^a P < 0.05, ^b P < 0.01, ^c P < 0.001 versus vehicle-treated db/db mouse values.