Figure 5.

On-rate penalties influence the resulting microtubule tip structure. (A) Examples of tapered microtubule end structures (displayed as two-dimensional sheets) from each of the three simulation conditions: no on-rate penalties (top); a single penalty to protofilaments with two lateral neighbors (middle); and model predicted penalties to protofilaments with both one and two lateral neighbors (bottom). (B) Probability density values of protofilament length standard deviations for tips in each simulation condition are shown. (C and D) The fraction of protofilaments with zero, one, or two lateral neighbors in (C) tapered tips from all three cases and (D) blunt (lighter) or tapered (darker) tips from simulations with one- and two-neighbor penalties.