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. 2013 Oct 22;14(Suppl 16):S9. doi: 10.1186/1471-2105-14-S16-S9

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Copyright © 2013 Pennisi et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Damage progression vs time in hill patients. Simulation of eight randomly-selected hill virtual patients. Simulation time is 5 years (18250 time-steps). Red lines represent activated unrecoverable damage, blue lines represent recoverable damage and black lines total damage (recoverable + unrecoverable). In this case it is possible to observe more frequent spikes in the reversible damage curves. Furthermore unrecoverable damage (that can be correlated with the appearing MS plaques) is also present.