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. Author manuscript; available in PMC: 2013 Dec 6.
Published in final edited form as: Annu Rev Immunol. 2013;31:10.1146/annurev-immunol-020711-074950. doi: 10.1146/annurev-immunol-020711-074950

Figure 2.

Figure 2

Phenotypes of murine DC progenitors. The illustration on the left suggests that the granulocyte macrophage progenitor (GMP) expresses high levels of c-kit and low levels of CX3CR1, Csf-1R (CD115), and Flt3 (CD135), whereas the macrophage DC progenitor (MDP) is positive for c-kit, CX3CR1, Csf-1R (CD115), and Flt3 (CD135). The common DC progenitor (CDP) expresses intermediate levels of c-kit and is positive for CX3CR1, Csf-1R (CD115), and Flt3 (CD135); pre-cDCs express no or low levels of c-kit but express CD115 and high levels of CD135. The table at the right summarizes the detailed phenotype of MDPs, CDPs, and pre-cDCs.