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. Author manuscript; available in PMC: 2013 Dec 6.
Published in final edited form as: Annu Rev Immunol. 2013;31:10.1146/annurev-immunol-020711-074950. doi: 10.1146/annurev-immunol-020711-074950

Figure 4.

Figure 4

Regulation of DC development and homeostasis in mice. This illustration summarizes the current model of the developmental pathways of both lymphoid tissue–resident and nonlymphoid tissue–resident murine DCs. Dashed lines indicate pathways that are likely but not yet definitively shown to operate in DC development. Cytokines and transcription factors that are important in each transition are indicated (HSC, hematopoietic stem cell; CMP, common myeloid progenitor; CLP, common lymphoid progenitor; MDP, macrophage DC progenitor; CDP, common DC progenitor; ETP, early thymic progenitor; mono, monocyte; LC, Langerhans cell).