Table 1.
Phenotype of mouse lymphoid and nonlymphoid tissue DCs
| Phenotypical marker | pDC | Lymphoid tissue cDC | Nonlymphoid tissue cDC | Langerhans cell | |||
|---|---|---|---|---|---|---|---|
| CD8+ cDC | CD11b+ cDC | CD103+ CD11b− cDC | CD103+ CD11b+ intestinal cDC | CD103− CD11b+ cDC | |||
| CD45 | + | + | + | + | + | + | + |
| CD11c | + | +++ | +++ | ++ | ++ | ++ | ++ |
| MHC class II | + | ++ | ++ | ++ | ++ | ++ | ++ |
| CD8 | subset | + | − | − | − | − | − |
| CD4 | + | − | +/− | − | − | − | ND |
| CD11b | − | − | + | − | + | + | + |
| CD103 | − | subset | − | ++ | ++ | − | − |
| Langerin | − | subset | − | + | − | − | ++ |
| EpCAM | − | − | − | − | − | − | ++ |
| B220 | + | − | − | − | − | − | − |
| CD24 | ND | ++ | + | ++ | ++ | +/− | ++ |
| Btla | + | ++ | + | ++ | + | +/− | ND |
| c-kit | − | + | + | + | + | +/− | ND |
| CD26 | + | + | + | + | + | +/− | ND |
| Xcr1 | − | + | − | + | − | − | − |
| CD36 | − | + | − | + | ND | − | − |
| Cystatin C | + | ++ | + | ND | ND | ND | ND |
| Clec9a (DNGR1) | + | ++ | − | ++ | − | − | − |
| Cadm1 (Necl2) | − | + | − | ND | ND | ND | ND |
| CD205 | − | ++ | + | ++ | ND | ND | ++ |
| CX3CR1 | − | subset | − | − | − | ++ | + |
| CD209 (dc-sign) | ++ | − | + | − | + | +/− | − |
| F4/80 | − | − | + | − | − | + | + |
| CD172a (Sirpa) | + | − | ++ | − | − | ++ | + |
| CD64 (Fc r1) | − | − | − | − | − | ++ | ND |
| Ly6C | ++ | − | − | − | − | +/− | − |
ND, not determined.