Table 9.

Group differences in effective connectivity during cognitive preparation for affective vs. neutral prosody.

Anatomical region	BA	MNI-coordinates (x, y, z)	T-value	p-value (SVC corr.)
Hypo-connectivity in PD patients
PD OFF < control
L superior parietal lobule
L inferior frontal gyrus	44, 45	− 46, 16, 4	3.52	0.004
R ventral striatum
R dorsal striatuma	–	14, 14, − 4	2.99	0.016
PD ON < control
L superior parietal lobule
L inferior frontal gyrus	45	− 34, 18, 6	3.36	0.007
Hyper-connectivity in PD patients
PD OFF > control
L supplementary motor area
L dorsolateral PFC	9	− 40, 26, 38	3.26	0.008
PD ON > control
L dorsolateral prefrontal cortex
L inferior frontal gyrus	47	− 48, 28, − 2	2.82	0.024
L caudate nucleus	–	− 6, 18, − 4	2.90	0.011
L supplementary motor area
L dorsolateral PFC	9	− 40, 24, 38	3.64	0.003

Seed regions are left-justified and target regions are tabulated.

^aNot illustrated.