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. Author manuscript; available in PMC: 2014 Oct 18.
Published in final edited form as: Biochem Biophys Res Commun. 2013 Aug 25;440(2):10.1016/j.bbrc.2013.08.055. doi: 10.1016/j.bbrc.2013.08.055

Fig. 3. HNG decreases a glutathione-based measure of oxidative stress while rapidly and persistently enhancing the activity of critical antioxidant enzymes.

Fig. 3

A The time course of change in the ratio of oxidized to reduced glutathione in lysates of cells treated with HNG (10 nM) (**p = 0.0007, 10 N per experiment, 4 experiments). Both B GPx (**p = 4.0×10−67 N per experiment, 4 experiments) and C catalase (*p = 0.0089, 18 N per experiment, 6 experiments) activities, normalized to total protein, following cell exposure to HNG (10 nM) and lysate prep. D Total cellular SOD activity (normalized to total protein) in lysates from cells exposed to HNG (10 nM) (*p = 0.004, 12 N per experiment, 4 experiments).