Table 3.
PedsQL 4.0 generic core scales from: (A). CKD child self-report, (B). parent/proxy reports (main caregivers), (C). “second” parent/proxy reports
| Physical functioning | Emotional functioning | Social functioning | School functioning | Overall HRQoL | |
|---|---|---|---|---|---|
| (A). children, n = 171 | |||||
| CT, n = 118 | 78.13 (63.28−7.5) | 65.0 (55.0−80.0) | 80.0 (60.0−90.5) | 65.0 (50.0−75.0) | 71.74 (58.15−80.98) |
| CKD 2–3, n = 75 | 78.13 (60.94−87.50) | 65 (55−77.5) | 80.0 (60−100) | 65.0 (50−80) | 69.02 (57.07−81.52) |
| CKD 4–5, n = 43 | 78.13 (65.63−84.38) | 65.0 (55−80) | 80.0 (65−93.75) | 65.0 (55−70) | 72.83 (60.87−79.08) |
| HD, n = 22 | 40.63 (18.75−65.63) | 52.5 (35.0−75.0) | 67.5 (50.0−80.0) | 47.5 (35.0−65.0) | 50.54 (40.22−64.13) |
| PD, n = 31 | 62.5 (50.0−75.0) | 70.0 (56.25−73.75) | 70.0 (50.0−90.0) | 62.5 (50.0−75.0) | 64.13 (51.09−75.0) |
| p value | 0.001 ab | 0.11 | 0.02 a | 0.07 | 0.001 b |
| (B). Parents/main caregivers, n = 201 | |||||
| CT, n = 136 | 75.00 (53.13−84.38) | 65.0 (51.25−75.0) | 75.0 (60.0−93.75) | 60.0 (45.0−70.0) | 66.3 (51.63−76.09) |
| CKD 2–3, n = 85 | 75.00 (50.0–87.5) | 65.0 (55.0–80.0) | 75.0 (60.0–95.0) | 60.0 (45.0−70.0) | 67.94 (51.09−78.26) |
| CKD 4–5, n = 51 | 71.88 (58.59–81.25) | 60.0 (50.0–70.0) | 70.0 (55.0–86.25) | 55.0 (45.0–65.0) | 65.22 (54.08–75.0) |
| HD, n = 24 | 51.56 (20.31–68.75) | 50.0 (37.5–65.0) | 62.5 (45.0–85.0) | 40.0 (35.0–60.0) | 49.46 (40.22–62.5) |
| PD, n = 41 | 56.24 (40.63–62.5) | 55.0 (40.0–70.0) | 55.0 (40.0–70.0) | 55.0 (35.0–65.0) | 54.35 (38.87–64.13) |
| p value | <0.0001 a | 0.006 a | 0.0003 a | 0.03 c | 0.0001 a,d |
| (C). “Second” parents n = 84 | |||||
| CT, n = 61 | 75.00 (56.25–84.38) | 60.0 (53.75–80.0) | 80.0 (63.75–95.0) | 65.0.0 (50.0–75.0) | 66.67 (53.26–79.62) |
| CKD 2–3 n = 39 | 78.13 (56.26–84.38) | 65.0 (60.0–80.0) | 80.0 (70.0–95.0) | 70.0 (50.0–75.0) | 69.05 (59.5–80.44) |
| CKD 4–5, n = 22 | 71.88 (53.13–81.25) | 55.0 (45.0–60.0) | 72.5 (60.0–80.0) | 60.0 (50.0–75.0) | 65.76 (50.0–73.91) |
| HD + PD n = 23 | 53.13 (41.41–67.97) | 55.0 (41.25–68.75) | 65.0 (56.25–80.0) | 55.0 (40–65) | 56.53 (49.18–63.04) |
| p value | 0.006 e | 0.06f, 0.02 h | 0.09 | 0.08 | 0.002 g |
Data were shown as median values and quartiles (first—third quartile). CT children on conservative treatment, HD children on haemodialysis, PD children on peritoneal dialysis
For children: aCT versus PD and HD; b HD versus PD and CT. For parents/main caregivers: aCT versus PD and HD; cCT versus HD; d PD versus HD. For “second” parents: eCT versus HD + PD; f CT versus HD + PD; gCT versus HD + PD; hCKD2–3 versus CKD4–5. Statistically significant differences are in bold (p < 0.05)