Table 3.
Major biological processes modified in MPA treated AGS cells
| Processes | ≥2 fold (1070) | >4 fold (85) | ||||
|---|---|---|---|---|---|---|
| UP: 620; Down: 450 | UP: 69; Down: 16 | |||||
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| # Genes | p-value | OR | # Genes | p-value | OR | |
| Angiogenesis | 23 | 0.183643 | 1.25 | 4 | 0.05803 | 2.88 |
| Lipid metabolic process | 84 | 0.001398 | 1.46 | 10 | 0.01807 | 2.34 |
| Response to stress | 219 | 4.47E-09 | 1.64 | 23 | 0.00079 | 2.47 |
| Cell cycle | 112 | 6.61E-06 | 1.64 | 6 | 0.52851 | 1.04 |
| Cell death | 142 | 5.22E-08 | 1.72 | 13 | 0.02280 | 2.04 |
| Cell proliferation | 129 | 1.45E-08 | 1.81 | 14 | 0.00272 | 2.64 |
| Cell migration | 59 | 0.00419 | 1.49 | 10 | 0.00130 | 3.52 |
| Regulation of phosphate metabolic process | 77 | 0.000128 | 1.63 | 9 | 0.01561 | 2.52 |
| Cellular response to stress | 92 | 3.85E-05 | 1.63 | 6 | 0.33588 | 1.30 |
| Small molecule metabolic process | 195 | 1.09E-06 | 1.52 | 21 | 0.00187 | 2.35 |
| Regulation of angiogenesis | 12 | 0.098609 | 1.57 | 2 | 0.12597 | 3.36 |
| Blood vessel morphogenesis | 30 | 0.06548 | 1.38 | 6 | 0.00784 | 3.73 |
| Cell motility | 64 | 0.002427 | 1.51 | 11 | 0.00061 | 3.65 |
| Regulation of protein metabolic process | 115 | 3.40E-07 | 1.75 | 10 | 0.05236 | 1.92 |