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Quantile-quantile plot for the genome-wide analysis of social communication difficulties in ALSPAC. The plot is based on genomic-control corrected P-values. Black circles depict the observed association signals, the white diagonal line represents the distribution of signals under the null hypothesis and the shaded area corresponds to the 95% confidence interval. A deviation of the observed from the expected distribution of signals is visible. λ, Genomic-control factor.
