Table 3.
Theoretic size of ROH for coefficient of inbreeding (F) expected from the total 2881 Mb autosomal genome (GRCh37/hg19)
| Mating type | Degree of relationship | Coefficient of inbreeding (F) | Theoretic proportion of identical by decent (%) | Expected ROH size and range (Mb) |
|---|---|---|---|---|
| Parent–child/brother-sister |
1st |
1/4 |
25 |
720 (540 ~ 1080) |
| Uncle-niece/aunt-nephew/double half cousins |
2nd |
1/8 |
12.5 |
360 (270 ~ 539) |
| First cousins/half uncle-niece |
3rd |
1/16 |
6.25 |
180 (135 ~ 269) |
| Half first cousins/first cousins once removed | 4th | 1/32 | 3.125 | 90 (68 ~ 134) |