Table 1.
Experimental design for each of the tested groups
| Pre-treatment (i.p. injection 10 min prior to behaviour) | ||||||
|---|---|---|---|---|---|---|
| Habituation Sessions (1 h behavioural assay) | Test sessions (1 h behavioural assay combined with microdialysis in groups 1–4) | |||||
| Group name (treatment/sweetener) | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 |
| Naïve glucose | VEH | VEH | VEH | VEH | VEH | 2-DG |
| Naïve sucralose | VEH | VEH | VEH | VEH | VEH | 2-DG |
| Recurrent glucose | VEH | 2-DG | VEH | 2-DG | VEH | 2-DG |
| Recurrent sucralose | VEH | 2-DG | VEH | 2-DG | VEH | 2-DG |
| Control glucose | VEH | VEH | VEH | VEH | VEH | VEH |
| Control sucralose | VEH | VEH | VEH | VEH | VEH | VEH |