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Mean (+ SD) plasma apixaban concentration vs. time profiles on days 1 and 7 for (A) twice daily and (B) once daily dosing regimens. 
, 2.5 mg twice daily; 
, 5 mg twice daily; 
, 10 mg twice daily; 
, 25 mg twice daily; 
, 10 mg once daily; 
, 25 mg once daily
