Table 1.
List of currently approved SLC families. The total numbers of members in each family are shown on the right. For detailed information about the SLC genes, please visit: http://www.bioparadigms.org.
| The HGNC Solute Carrier Family Series | Total 2004 | Total 2013 |
|---|---|---|
| SLC1: The high affinity glutamate and neutral amino acid transporter family | 7 | 7 |
| SLC2: The facilitative GLUT transporter family | 14 | 14 |
| SLC3: The heavy subunits of the heteromeric amino acid transporters | 2 | 2 |
| SLC4: The bicarbonate transporter family | 10 | 10 |
| SLC5: The sodium glucose cotransporter family | 8 | 12 |
| SLC6: The sodium- and chloride-dependent neurotransmitter transporter family | 16 | 21 |
| SLC7: The cationic amino acid transporter/glycoprotein-associated amino-acid transporter family | 14 | 14 |
| SLC8: The Na+/Ca2+ exchanger family | 3 | 3 |
| SLC9: The Na+/ H+ exchanger family | 8 | 13 |
| SLC10: The sodium bile salt cotransport family | 6 | 7 |
| SLC11: The proton coupled metal ion transporter family | 2 | 2 |
| SLC12: The electroneutral cation-Cl cotransporter family | 9 | 9 |
| SLC13: The human Na+-sulfate/carboxylate cotransporter family | 5 | 5 |
| SLC14: The urea transporter family | 2 | 2 |
| SLC15: The proton oligopeptide cotransporter family | 4 | 5 |
| SLC16: The monocarboxylate transporter family | 14 | 14 |
| SLC17: The vesicular glutamate transporter family | 8 | 9 |
| SLC18: The vesicular amine transporter family | 3 | 4 |
| SLC19: The folate/thiamine transporter family | 3 | 3 |
| SLC20: The type III Na+-phosphate cotransporter family | 2 | 2 |
| SLC21/SLCO: The organic anion transporting family | 11 | 12 |
| SLC22: The organic cation/anion/zwitterion transporter family | 18 | 23 |
| SLC23: The Na+-dependent ascorbic acid transporter family | 4 | 4 |
| SLC24: The Na+/(Ca2+–K+) exchanger family | 5 | 6 |
| SLC25: The mitochondrial carrier family | 27 | 53 |
| SLC26: The multifunctional anion exchanger family | 10 | 11 |
| SLC27: The fatty acid transport protein family | 6 | 6 |
| SLC28: The Na+-coupled nucleoside transport family | 3 | 3 |
| SLC29: The facilitative nucleoside transporter family | 4 | 4 |
| SLC30: The zinc efflux family | 9 | 10 |
| SLC31: The copper transporter family | 2 | 2 |
| SLC32: The vesicular inhibitory amino acid transporter family | 1 | 1 |
| SLC33: The Acetyl-CoA transporter family | 1 | 1 |
| SLC34: The type II Na+-phosphate cotransporter family | 3 | 3 |
| SLC35: The nucleoside-sugar transporter family | 17 | 30 |
| SLC36: The proton-coupled amino acid transporter family | 4 | 4 |
| SLC37: The sugar-phosphate/phosphate exchanger family | 4 | 4 |
| SLC38: The System A & N, sodium-coupled neutral amino acid transporter family | 6 | 11 |
| SLC39: The metal ion transporter family | 14 | 14 |
| SLC40: The basolateral iron transporter family | 1 | 1 |
| SLC41: The MgtE-like magnesium transporter family | 3 | 3 |
| SLC42: The Rh ammonium transporter family (pending) | 3 | 3 |
| SLC43: Na+-independent, system-L like amino acid transporter family | 2 | 3 |
| SLC44: Choline-like transporter family | 5 | |
| SLC45: Putative sugar transporter family | 4 | |
| SLC46: Folate transporter family | 3 | |
| SLC47: Multidrug and Toxin Extrusion (MATE) family | 2 | |
| SLC48: Heme transporter family | 1 | |
| SLC49: FLVCR-related transporter family | 4 | |
| SLC50: Sugar efflux transporters | 1 | |
| SLC51: Transporters of steroid-derived molecules | 2 | |
| SLC52: Riboflavin transporter family | 3 | |
| Total | 298 | 395 |