Table 2.

Initial heating rates of uncoated and lipid-coated SPIONs following exposure to an alternating magnetic field

Particle concentration/suspension vehicle	Initial heating rate (°C/min)
	MFG-1000 at 7.0 mT (1 MHz)		MHS at 16.6 mT (13.6 MHz)
	Uncoated SPIONs	Lipid-coated SPIONs	Uncoated SPIONs	Lipid-coated SPIONs
1 mg/mL (Citrate buffer)	0.88 ± 0.02	1.26 ± 0.03**	0.35 ± 0.01	0.61 ± 0.02**
0.24 mg/mL (Citrate buffer)	0.90 ± 0.02	1.05 ± 0.04	0.36 ± 0.02	0.56 ± 0.01
0.02 mg/mL (Citrate buffer)	0.95 ± 0.03*	0.94 ± 0.02	0.47 ± 0.01*	0.46 ± 0.01
0.02 mg/mL (HBSS)	0.66 ± 0.02	0.94 ± 0.01	0.33 ± 0.01	0.44 ± 0.02
0.02 mg/mL (PBS)	0.55 ± 0.02	0.92 ± 0.02	0.20 ± 0.01	0.43 ± 0.01

Data are shown as mean ± SD (n = 3).

*Significantly different from uncoated control SPIONs at 0.02 mg/mL (p < 0.05).

**Significantly different from lipid-coated SPIONs at 0.02 mg/mL in citrate buffer (p < 0.05).