Table 5. Comparison of increases and decreases in AA gene expression between presented results and previous findings.
Gene | Results (674 Genes) | Martin (17 of 424 Genes) | Field (3 of 27 Genes) | Grunda (1 of 20 Genes) |
---|---|---|---|---|
AK2 | increase | increase | ||
APP | increase | increase | ||
BUB1 | increase | increase | ||
CKS2 | increase | increase | ||
CRYBB2 | increase | increase | increase | |
CXCL10 | increase | increase | ||
DNAJC15 | increase | increase | ||
DUT | increase | decrease | ||
ESPL1 | increase | increase | ||
ESR1 | decrease | decrease | ||
HLA-DQB1 | increase | increase | ||
ISG20 | increase | increase | ||
KIF20A | increase | increase | ||
MRPL48 | increase | increase | ||
SNED1 | decrease | decrease | ||
TAP2 | increase | increase | ||
UBE2C | increase | increase | ||
ZIC1 | decrease | increase | ||
ZNF395 | decrease | decrease | decrease |
Italicized genes were inconsistent with literature while blank entries were not observed. Comparisons are an increase in decrease in expression of AA samples relative to CA samples. The number of genes in parentheses refers to the number of genes in common with the presented results compared to the total number of differentially expressed genes from each study. Gene names: AK2 - adenylate kinase 2; APP - amyloid beta (A4) precursor protein; BUB1 - BUB1 mitotic checkpoint serine/threonine kinase; CKS2 - CDC28 protein kinase regulatory subunit 2; CRYBB2 - crystallin, beta B2; CXCL10 - chemokine (C-X-C motif) ligand 10; DNAJC15 - DnaJ (Hsp40) homolog, subfamily C, member 15; DUT - deoxyuridine triphosphatase; ESPL1 - extra spindle pole bodies homolog 1 (S. cerevisiae); ESR1 - estrogen receptor 1; HLA-DQB1 - major histocompatibility complex, class II, DQ beta 1; ISG20 - interferon stimulated exonuclease gene 20kDa; KIF20A - kinesin family member 20A; MRPL48 - mitochondrial ribosomal protein L48; SNED1 - sushi, nidogen and EGF-like domains 1; TAP2 - transporter 2, ATP-binding cassette, sub-family B (MDR/TAP); UBE2C - ubiquitin-conjugating enzyme E2C; ZIC1 - Zic family member 1; ZNF395 - zinc finger protein 395.