Table 5.
Mean FIC values of interactions between six LC-PUFAs and six topical antimicrobial agents against S. aureus ATCC43300 showing that there was synergy (FIC ≤ 0.5) between BPO with three LC-PUFAs and NEO with five LC-PUFAs. Values in bold indicate synergy; n = 2; mean ± one standard deviation.
| S. aureus | DGLA | DHA | EPA | GLA | HETrE | 15-OHEPA |
|---|---|---|---|---|---|---|
| BPO | 0.44 ± 0.09 | 2.00 ± 0.00 | 1.00 ± 0.00 | 0.56 ± 0.09 | 0.50 ± 0.00 | 0.44 ± 0.09 |
| SA | 2.00 ± 0.00 | 1.25 ± 0.35 | 0.88 ± 0.18 | 0.88 ± 0.18 | 0.88 ± 0.18 | 1.00 ± 0.00 |
| FUS | 0.81 ± 0.27 | 2.00 ± 0.00 | 1.13 ± 0.18 | 1.50 ± 0.71 | 1.50 ± 0.71 | 2.00 ± 0.00 |
| MUP | 1.50 ± 0.71 | 1.50 ± 0.00 | 2.00 ± 0.00 | 2.25 ± 0.35 | 2.00 ± 0.00 | 1.38 ± 0.88 |
| NEO | 0.28 ± 0.13 | 0.56 ± 0.09 | 0.38 ± 0.00 | 0.19 ± 0.00 | 0.38 ± 0.00 | 0.34 ± 0.04 |
| POL | 1.78 ± 1.72 | 2.00 ± 0.00 | 2.00 ± 0.00 | 1.06 ± 0.62 | 0.75 ± 0.00 | 0.94 ± 0.27 |