Table 1.
Clinical data
| Pat. | Age | Sex | Dur. | RUE (75) | LUE (75) | RLE (45) | LLE (45) | Bulbar (0–14) | Babinski (0–2) | Spasticity (0–32) | Reflexes (0–13) | ALSFRS-R | ALSFRS-R PR/M6 | ALSFRS-R PR/M(t) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
59 |
m |
30 |
68 |
69 |
41 |
41 |
2 |
0 |
0 |
0 |
43 |
0.5 |
0.2 |
| 2 |
59 |
m |
13 |
75 |
64 |
31 |
27 |
0 |
0 |
0 |
0 |
37 |
1.8 |
0.8 |
| 3 |
31 |
m |
17 |
64 |
62 |
45 |
45 |
0 |
2 |
0 |
12 |
42 |
1.2 |
0.4 |
| 4 |
68 |
m |
22 |
75 |
73 |
45 |
42 |
2 |
2 |
4 |
4 |
40 |
0.7 |
0.4 |
| 5 |
65 |
m |
25 |
72 |
75 |
26 |
16 |
0 |
1 |
0 |
6 |
37 |
0.7 |
0.4 |
| 6 |
53 |
m |
38 |
74 |
75 |
26 |
23 |
0 |
0 |
0 |
0 |
43 |
0.2 |
0.1 |
| 7 |
34 |
w |
18 |
70 |
71 |
45 |
45 |
4 |
2 |
0 |
12 |
39 |
1.0 |
0.5 |
| 8 |
62 |
m |
18 |
63 |
73 |
45 |
45 |
4 |
0 |
0 |
12 |
40 |
0.7 |
0.4 |
| 9 |
49 |
m |
19 |
54 |
55 |
45 |
45 |
0 |
2 |
0 |
0 |
41 |
0.3 |
0.4 |
| 10 |
60 |
m |
30 |
58 |
57 |
45 |
45 |
2 |
2 |
0 |
5 |
33 |
1.5 |
0.5 |
| 11 |
77 |
m |
34 |
70 |
71 |
22 |
37 |
0 |
2 |
2 |
12 |
33 |
1.7 |
0.4 |
| 12 |
63 |
w |
12 |
75 |
75 |
45 |
45 |
3 |
0 |
0 |
11 |
45 |
0.2 |
0.3 |
| 13 |
66 |
m |
23 |
61 |
71 |
44 |
44 |
0 |
1 |
0 |
0 |
48 |
0.0 |
0.0 |
| 14 | 72 | m | 25 | 69 | 71 | 40 | 41 | 3 | 2 | 4 | 6 | 48 | 1.0 | 0.3 |
Pat. = patient; Dur. = duration in months; m = man, w = woman; RUE, LUE, RLE, LLE: right upper, left upper, right lower, left lower extremity; ALSFRS-R: ALS functional rating scale- revised, PR/M6 progression rate for the 6 months prior to MR-scanning, PR/M(t) progression rate per month for the entire duration of the disease.