Table 2.
Mean progression-free survival and overall survival for various characteristics based on Kaplan-Meier analysisa
|
Variables |
Mean PFS |
P |
Mean OS |
P |
|---|---|---|---|---|
| (95% CI) | (95% CI) | |||
| BMI |
|
0.077 |
|
0.701 |
| <23 kg/m2 |
79.4 (74.6 to 84.2) |
|
71.9 (66.9 to 76.9) |
|
| ≥23 kg/m2 |
77.2 (72.9 to 81.4) |
|
75.0 (70.8 to 79.3) |
|
| Mean age |
|
0.628 |
|
0.727 |
| <60 years |
78.9 (74.0 to 83.8) |
|
74.6 (69.6 to 79.6) |
|
| ≥60 years |
78.3 (74.0 to 82.6) |
|
74.0 (69.7 to 78.3) |
|
| Gender |
|
0.112 |
|
0.043 |
| Male |
75.3 (71.1 to 79.6) |
|
71.1 (67.0 to 75.1) |
|
| Female |
81.3 (76.9 to 86.8) |
|
77.3 (72.0 to 82.6) |
|
| Diabetes |
|
0.158 |
|
0.884 |
| Yes |
70.2 (61.9 to 78.5) |
|
69.2 (60.5 to 77.8) |
|
| No |
80.3 (76.8 to 83.8) |
|
74.9 (71.3 to 78.4) |
|
| Alcohol |
|
0.291 |
|
0.088 |
| Yes |
75.1 (68.3 to 81.9) |
|
69.2 (62.6 to 75.8) |
|
| No |
80.1 (76.4 to 83.7) |
|
76.2 (72.4 to 80.0) |
|
| Smoking |
|
0.222 |
|
0.007 |
| Yes |
74.7 (68.5 to 80.9) |
|
67.9 (62.0 to 73.8) |
|
| No |
80.3 (76.5 to 84.1) |
|
76.9 (72.9 to 80.8) |
|
| Site |
|
0.289 |
|
0.788 |
| Colon |
78.4 (74.0 to 82.8) |
|
73.2 (68.8 to 77.7) |
|
| Rectum |
77.5 (73.0 to 82.1) |
|
74.0 (69.5 to 78.5) |
|
| Tumor size |
|
0.903 |
|
0.015 |
| <5 cm |
79.8 (75.8 to 83.8) |
|
78.1 (74.0 to 82.3) |
|
| ≥5 cm |
77.4 (72.0 to 82.9) |
|
69.2 (64.0 to 74.4) |
|
| Pathological type |
|
0.291 |
|
2.5 × 10–4 |
| Adenocarcinoma |
79.9 (76.5 to 83.3) |
|
76.7 (73.2 to 80.3) |
|
| Others |
71.7 (61.5 to 82.0) |
|
59.2 (50.2 to 68.3) |
|
| Differentiation |
|
0.112 |
|
4.0 × 10–5 |
| Grade 3/4 |
80.4 (77.0 to 83.9) |
|
78.0 (74.6 to 81.4) |
|
| Grade 1/2 |
67.3 (59.1 to 75.4) |
|
57.1 (49.7 to 64.5) |
|
| Lymph nodes harvested |
|
0.910 |
|
0.575 |
| ≥12 |
79.3 (74.4 to 84.2) |
|
73.4 (68.4 to 78.5) |
|
| <12 |
76.3 (72.2 to 80.3) |
|
73.0 (69.0 to 77.1) |
|
| Lymph nodes positive |
|
1.5 × 10–7 |
|
2.0 × 10–13 |
| Positive |
67.8 (61.9 to 73.8) |
|
60.9 (55.6 to 66.3) |
|
| Negative | 85.4 (81.8 to 89.0) | 84.6 (80.9 to 88.3) |
aBMI, body mass index; CI, confidence interval; OS, overall survival; PFS, progression-free survival.