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. 2013 Sep;11(Suppl 4):s86–s93. doi: 10.2450/2013.014s

Table I.

Antithrombin, brief fact sheet.

ATCa B01AB02
Definition Antithrombin
U/Mb International Units (I.U.)
Therapeutic indications AT administration is used for prophylaxis and therapy for thromboembolic phenomena due to:
  • - congenital deficiencies, in particular in case of surgery, pregnancy or childbirth;

  • - acquired deficiencies, in particular in case of:

    • - risk of capillary microthrombosis or ongoing capillary microthrombosis due to disseminated intravascular coagulation (e.g. polytrauma, septic complications, shock, pre-eclampsia and other disease states due to acute consumption coagulopathies);

    • - risk of thrombosis or ongoing thrombosis in patients with nephrotic syndrome or enteropathies;

    • - surgery and bleeding in patients with severe liver failure, especially if a clotting factor concentrates replacement therapy is required (prothrombin complex).

NHS classc H
Management information -
a

Anatomical Therapeutic Chemical Classification System. The World Health Organization system classifies all therapeutic medicinal products. The purpose is to serve as a tool for medicinal products utilisation research in order to improve the quality of their use. Medicinal products are classified into five different levels;

b

Unit of Measure;

c

National Health Service Class.

All medicinal products are divided in classes according to the level of reimbursement by the National Health Service. Class A includes all medicinal products funded by the National Health Service; class H includes all medicinal products distributed only by hospital pharmacies within the regional healthcare services; class C refers to all medicinal products sa paid for by private out-of-pocket expense.