Table 3.

Multivariate analysis

	Oral BuCy vs Cy/TBI RR (95% CI)	IV BuCy vs Cy/TBI RR (95% CI)	Oral BuCy vs IV BuCy RR (95% CI)	Overall P value
aGVHD III-IV*	0.72 (0.53-0.98)	0.72 (0.51-1.02)	1.00 (0.67-1.49)	.048
cGVHD†	1.01 (0.73-1.39)	1.13 (0.87-1.47)	0.89 (0.58-1.37)	.65
NRM‡	0.72 (0.52-1.01)	0.58 (0.39-0.86)	1.24 (0.79-1.95)	.011
Relapse (≤1 y)§	0.81 (0.59-1.11)	1.06 (0.76-1.49)	0.76 (0.52-1.12)	.31
Relapse (>1 y)§	1.22 (0.78-1.90)	0.24 (0.084-0.66)	5.19 (1.85-14.57)	.0074
LFS‖	0.87 (0.72-1.06)	0.70 (0.55-0.88)	1.25 (0.96-1.62)	.0096
OS‖	0.78 (0.60-1.01)	0.68 (0.52-0.88)	1.15 (0.85-1.56)	.0084

Other significant factors in the multivariate model are noted by symbol. Bold indicates P value < .05. aGVHD, acute GVHD; cGVHD, chronic GVHD.

*Sex, donor type.

^†Donor type, recipient age, donor and recipient sex match, and graft type.

^‡Recipient age, KPS, donor type, time from diagnosis to transplant.

^§KPS and Cytogenetic risk group.

^‖Recipient age, KPS, donor type, Cytogenetic risk group.