Table 5.
Notable regions classified as growth-defect
| Orf Ids | Included genes | Insertion density | Average reads | Average nonzero reads |
|---|---|---|---|---|
| Rv0015c, Rv0016c |
pknA, pbpA |
0.21 |
6.7 |
32.3 |
| Rv0467 |
icl |
0.23 |
4.0 |
17.6 |
| Rv2379c |
mbtF |
0.23 |
3.2 |
14.0 |
| Rv2380c, Rv2381c, Rv2382c |
mbtE, mbtD, mbtC |
0.29 |
6.4 |
21.7 |
| Rv3841 |
bfrB |
0.24 |
4.1 |
17.2 |
| Rv0126 |
treS |
0.26 |
6.6 |
25.8 |
| Rv1097c, Rv1098c, Rv1099c | fumC, glpX | 0.10 | 4.0 | 40.0 |
Notable Regions labeled as 'growth-defect’ (GD) by the HMM, in which there is a suppression of reads, suggesting an under-representation of transposon insertions in the library. Note that a lower read count is reflected in both a low read count (typically around 10–20, compared to the ∼ 250 average across the whole genome) and a low insertion density (∼ 0.20 compared to 0.54 for the whole genome).