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. 2012 Jul 20;45(11):1060–1065. doi: 10.1590/S0100-879X2012007500119

Table 1. Effects of nifedipine on systolic tension, coronary flow and maximal (+dT/dt) and minimal (-dT/dt) contractility of isolated rat hearts from Wistar audiogenic rats and Wistar rats.

WAR WAR + N20 WAR + N40 Wistar Wistar + N20 Wistar + N40
ST 10.0 ± 0.6 9.7 ± 1.1 8.5 ± 0.8 9.5 ± 0.6 9.1 ± 0.6 8.8 ± 0.9
CF 7.89 ± 0.9 7.96 ± 0.5 7.11 ± 1.0 8.64 ± 0.8 8.50 ± 0.5 8.21 ± 0.6
+dT/dt 211 ± 15 196 ± 22 212 ± 19 192 ± 18 182 ± 12 173 ± 10
-dT/dt 231 ± 18 244 ± 24 204 ± 18 205 ± 16 202 ± 20 197 ± 7

Data are reported as means ± SEM for 6 rats per group. No significant differences were observed among any of the groups. N20 and N40 = 20 and 40 mg/kg nifedipine, respectively; ST = systolic tension (g); CF = coronary flow (mL/min); WAR = Wistar audiogenic rats.