Figure 1. Masson's trichrome-stained histological sections (A and B) and immunolocalization of vimentin (C and D) and ED1⁺ cells (macrophages/monocytes; E and F) from the renal cortex of rats treated with gentamicin (A, C, E) or gentamicin+PAG (B, D, F), 2 days after the end of the treatment. Note the presence of tubular necrosis (black arrow) and the increase of relative interstitial area in A (asterisk). This alteration was less intense in B. Vimentin expression (white arrows) and the number of ED1⁺ cells (dotted arrows) were higher in C and E than in D and F. Magnification bars = 20 µm.