Table 2. Performance of PCR-Pra for the detection of Mycobacterium leprae in urine according to the clinical form of non-treated patients and patients under treatment.
| PCR positivity (%) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Non-treated patients | Patients under treatment | Total | Control group | |||||||||
| II | TT | BB | LL | Total | II | TT | BB | LL | Total | Total | ||
| PCR-Pra | (0/2) | 75.0 (6/8) | 28.6 (2/7) | 30.0 (6/20) | 37.8 (14/37) | (0/0) | 75.0 (3/4) | 57.1 (4/7) | 52.0 (13/25) | 55.5 (20/36) | 46.6 (34/73) | (0/50) |
The number of individuals is given in parentheses. II = indeterminate leprosy; TT = tuberculoid leprosy; BB = borderline leprosy; LL = lepromatous leprosy. P = 0.1306 (McNemar test), PCR results vs patients with the TT form. P = 0.2386 (McNemar test), PCR results vs patients with the LL form. P = 0.2889 (McNemar test), PCR results vs non-treated patients with the TT form and the LL form. P = 0.0033 (McNemar test), PCR results vs patients with the TT and LL forms under treatment.