Table 3.
Comparison of different methods for classifying exposed/buried residues on 392 interface TM residues of the independent test set by rASA derived from both subunit structure and complete structure (in parentheses)
| Measurements | TMexpo | MPRAP | TMX | Rhythm (membrane-coil) | Rhythm (channel) |
|---|---|---|---|---|---|
| MCC |
0.14 (0.22) |
0.12 (0.25) |
0.13 (0.17) |
0.08 (−0.06) |
0.19 (0.28) |
| Sensitivity |
73.11% (81.25%) |
56.29% (67.23%) |
66.17% (72.78%) |
67.72% (63.22%) |
66.10% (77.97%) |
| Specificity |
48.57% (38.50%) |
64.71% (57.59%) |
55.88% (43.98%) |
45.00% (30.77%) |
64.29% (49.32%) |
| Precision |
93.55% (55.91%) |
94.00% (59.50%) |
93.70% (55.04%) |
90.68% (46.61%) |
93.98% (55.42%) |
| Accuracy | 70.92% (59.44%) | 57.07% (62.23%) | 65.23% (57.95%) | 65.17% (46.63%) | 65.91% (62.12%) |