Table 2.
Anthropometrical, biochemical variables and blood pressure according to CILP2 genotypes in Slovak women.
| Parameter | CILP2 genotype | Menopause status ∗ CILP2 | ||||
|---|---|---|---|---|---|---|
| GG | GT/TT | F | P a | P b | P | |
| n = 299 | n = 31 | |||||
| Weight (kg) | 73.35 ± 15.61 | 71.97 ± 12.05 | 0.303 | 0.583 | ||
| WC (cm) | 85.66 ± 14.55 | 84.20 ± 11.42 | 0.479 | 0.489 | ||
| HC (cm) | 104 ± 11.11 | 105 ± 8.66 | 0.012 | 0.911 | ||
| BMI (kg/m2) | 27.47 ± 5.68 | 26.43 ± 4.56 | 1.203 | 0.274 | ||
| WHR | 0.82 ± 0.08 | 0.80 ± 0.08 | 1.386 | 0.240 | ||
| GMT (µkat/L) | 0.40 ± 0.40 | 0.47 ± 0.39 | 0.910 | 0.341 | ||
| ALT (µkat/L) | 0.33 ± 0.20 | 0.37 ± 0.23 | 0.949 | 0.331 | ||
| UA (µmol/L) | 255 ± 65.55 | 256 ± 67.38 | 0.000 | 0.996 | ||
| TC (mmol/L) | 5.45 ± 1.05 | 5.10 ± 0.83 | 3.629 | 0.058 | ||
| TG (mmol/L) | 1.42 ± 0.89 | 1.17 ± 0.47 | 2.733 | 0.099 | ||
|
| ||||||
| n = 298 | n = 31 | |||||
|
| ||||||
| Bilirubin (µmol/L) | 8.82 ± 4.13 | 9.58 ± 4.47 | 0.963 | 0.327 | ||
| Glucose (mmol/L) | 5.02 ± 1.41 | 4.79 ± 0.82 | 1.032 | 0.310 | ||
|
| ||||||
| n = 276 | n = 28 | n = 304 | ||||
|
| ||||||
| HDL-C (mmol/L) | 1.54 ± 0.40 | 1.76 ± 0.53 | 7.810 | 0.006 | 0.007 | 0.882 |
| LDL-C (mmol/L) | 3.29 ± 0.96 | 2.84 ± 0.72 | 6.076 | 0.014 | 0.016 | 0.557 |
| apoA1 (g/L) | 1.70 ± 0.43 | 1.77 ± 0.27 | 0.689 | 0.407 | ||
| apoB (g/L) | 0.95 ± 0.26 | 0.80 ± 0.18 | 9.289 | 0.003 | 0.004 | 0.821 |
| apoB-to-apoA1 | 0.58 ± 0.18 | 0.47 ± 0.14 | 10.572 | 0.001 | 0.002 | 0.500 |
| TC-to-HDL-C | 3.77 ± 1.13 | 3.13 ± 0.93 | 8.601 | 0.004 | 0.005 | 0.304 |
| non-HDL-C | 3.92 ± 1.07 | 3.38 ± 0.81 | 7.497 | 0.007 | 0.009 | 0.485 |
| LDL-C-to-HDL-C | 2.29 ± 0.92 | 1.78 ± 0.77 | 8.454 | 0.004 | 0.006 | 0.352 |
| log(TG-to-HDL-C) | −0.09 ± 0.29 | −0.18 ± 0.26 | 2.989 | 0.085 | ||
|
| ||||||
| n = 269 | n = 29 | |||||
|
| ||||||
| sBP (mmHg) | 122 ± 17.16 | 126 ± 16.07 | 0.956 | 0.329 | ||
| dBP (mmHg) | 79 ± 11.54 | 79 ± 10.38 | 0.052 | 0.820 | ||
WC: waist circumference; HC: hip circumference; BMI: body mass index; WHR: waist-to-hip ratio; GMT: gamma glutamyl transpeptidase, ALT: alanine aminotransferase; UA: uric acid; TC: total cholesterol; TG: triglycerides, HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein; apoA1: apolipoprotein A1; apoB: apolipoprotein B; sBP: systolic blood pressure; dBP: diastolic blood pressure. Values represent mean ± SD. aAdjusted for age; badjusted for age, BMI, and WHR.