Table 4.
Anthropometrical, biochemical variables and blood pressure according to ACE genotypes in Slovak women.
| Parameter | AC E genotypes | DD versus ID versus II | II versus ID/DD | Menopausal status ∗ ACE | |||||
|---|---|---|---|---|---|---|---|---|---|
| DD | ID | II | F | P a | F | P a | P b | P | |
| n = 111 | n = 130 | n = 73 | |||||||
| Weight (kg) | 73.30 ± 15.91 | 72.86 ± 15.27 | 73.61 ± 15.10 | 0.062 | 0.940 | 0.024 | 0.877 | ||
| WC (cm) | 84.36 ± 13.84 | 85.78 ± 14.95 | 87.38 ± 14.35 | 0.697 | 0.499 | 1.018 | 0.314 | ||
| HC (cm) | 105 ± 11.54 | 104 ± 10.30 | 105 ± 11.20 | 0.549 | 0.578 | 0.347 | 0.556 | ||
| BMI (kg/m2) | 27.24 ± 5.85 | 27.41 ± 5.56 | 27.56 ± 5.34 | 0.021 | 0.979 | 0.027 | 0.868 | ||
| WHR | 0.80 ± 0.07 | 0.82 ± 0.09 | 0.83 ± 0.08 | 2.422 | 0.090 | 1.162 | 0.282 | ||
| GMT (µkat/L) | 0.41 ± 0.38 | 0.39 ± 0.35 | 0.42 ± 0.51 | 0.135 | 0.873 | 0.121 | 0.729 | ||
| ALT (µkat/L) | 0.34 ± 0.22 | 0.33 ± 0.20 | 0.30 ± 0.17 | 1.109 | 0.331 | 1.990 | 0.159 | ||
| UA (µmol/L) | 257 ± 69.37 | 254 ± 64.61 | 258 ± 66.42 | 0.096 | 0.908 | 0.031 | 0.860 | ||
| TC (mmol/L) | 5.49 ± 1.03 | 5.50 ± 1.07 | 5.23 ± 0.97 | 2.189 | 0.114 | 4.393 | 0.037 | 0.035 | 0.377 |
| TG (mmol/L) | 1.49 ± 1.04 | 1.34 ± 0.68 | 1.43 ± 0.89 | 1.091 | 0.337 | 0.008 | 0.927 | ||
|
| |||||||||
| n = 110 | n = 130 | n = 73 | |||||||
|
| |||||||||
| Bilirubin (µmol/L) | 8.62 ± 4.06 | 9.38 ± 4.80 | 8.53 ± 3.33 | 1.354 | 0.260 | 0.712 | 0.399 | ||
|
| |||||||||
| n = 111 | n = 130 | n = 72 | |||||||
|
| |||||||||
| Glucose (mmol/L) | 5.02 ± 1.38 | 4.98 ± 1.56 | 5.01 ± 1.00 | 0.070 | 0.933 | 0.008 | 0.928 | ||
|
| |||||||||
| n = 103 | n = 118 | n = 68 | |||||||
|
| |||||||||
| HDL-C (mmol/L) | 1.57 ± 0.41 | 1.60 ± 0.46 | 1.54 ± 0.38 | 0.393 | 0.676 | 0.480 | 0.489 | ||
| LDL-C (mmol/L) | 3.27 ± 0.99 | 3.33 ± 0.95 | 3.03 ± 0.83 | 2.619 | 0.075 | 5.011 | 0.026 | 0.027 | 0.975 |
| apoA1 (g/L) | 1.73 ± 0.26 | 1.75 ± 0.59 | 1.62 ± 0.24 | 1.855 | 0.158 | 3.646 | 0.057 | ||
| apoB (g/L) | 0.95 ± 0.25 | 0.95 ± 0.28 | 0.89 ± 0.20 | 1.603 | 0.203 | 3.172 | 0.076 | ||
| apoB-to-apoA1 | 0.57 ± 0.19 | 0.57 ± 0.18 | 0.56 ± 0.17 | 0.019 | 0.981 | 0.035 | 0.851 | ||
| TC-to-HDL-C | 3.74 ± 1.14 | 3.69 ± 1.12 | 3.58 ± 1.10 | 0.548 | 0.579 | 0.981 | 0.323 | ||
| non-HDL-C | 3.94 ± 1.09 | 3.93 ± 1.06 | 3.66 ± 0.96 | 2.268 | 0.105 | 4.549 | 0.034 | 0.023 | 0.951 |
| LDL-C-to-HDL-C | 2.26 ± 0.95 | 2.25 ± 0.88 | 2.12 ± 0.90 | 0.660 | 0.517 | 1.319 | 0.252 | ||
| log(TG-to-HDL-C) | −0.08 ± 0.29 | −0.12 ± 0.30 | −0.10 ± 0.29 | 0.492 | 0.612 | 0.004 | 0.949 | ||
|
| |||||||||
| n = 98 | n = 118 | n = 70 | |||||||
|
| |||||||||
| sBP (mmHg) | 123 ± 17.77 | 123 ± 18.71 | 121.03 ± 13.65 | 0.781 | 0.459 | 1.509 | 0.220 | ||
| dBP (mmHg) | 79 ± 9.41 | 79 ± 11.20 | 78.04 ± 14.56 | 0.260 | 0.771 | 0.451 | 0.503 | ||
WC: waist circumference; HC: hip circumference; BMI: body mass index; WHR: waist-to-hip ratio; GMT: gamma glutamyl transpeptidase, ALT: alanine aminotransferase; UA: uric acid; TC: total cholesterol; TG: triglycerides, HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein; apoA1: apolipoprotein A1; apoB: apolipoprotein B; sBP: systolic blood pressure; dBP: diastolic blood pressure. Values represent mean ± SD. aAdjusted for age; badjusted for age, BMI, and WHR.