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. 2013 Apr 3;7:1–8. doi: 10.2174/2213988501307010001

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© Sheth et al.; Licensee Bentham Open.

This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

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Fig. (2) — Comparison of concentration responses of 2-iodomelatonin (a MT1 melatonin receptor agonist) determined in the single assay to these in the multiplexed assay. (A) EC₅₀ values of 2-iodomelatonin were 19.4 nM and 13.8 nM measured in the FLIPR calcium assay in the single assay format (FLIPR) and multiplexed assay format (Multip), respectively. (B) EC₅₀ values of 2-iodomelatonin were 5.38 pM and 3.48 pM determined in the NFAT beta-lactamase reporter gene assay in the single assay format (BLA) and multiplexed assay format (Multip), respectively.