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Stereological analysis of vehicle and GM-CSF-treated animals. Average cell counts per mm2 retinal area is shown for each condition. The rAION induction resulted in a 42.9% RGC loss in vehicle-treated animals versus a 33.9% RGC loss in GM-CSF-treated, animals when calculated against their contralateral control eyes. The difference in overall RGC numbers in the treated eyes between the two treatment groups is nonsignificant (P = 0.91, 2-tailed t-test, n = 9 animals/treatment group).
