Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Illustration of clinical features representing a wound paradoxical reaction.a-b: Buruli ulcer lesion posterior calf at commencement of antibiotic treatment with induration 40x42 mm diameter (a). Lesion after 5 weeks antibiotic treatment complicated by a paradoxical reaction manifest by increased induration around lesion (60x40 mm diameter), increased serous discharge and new ulceration adjacent to initial lesion (b).
