Figure 3.

Reduced bacterial concentrations in lungs and blood in AAT transgenic mice following P.aer pneumonia. Six transgenic (AAT^+/+) mice and six C57Bl/6 non-transgenic control (Control) mice were infected with inhaled P.aer. After 24 h, mice were euthanized and lung tissues and blood samples collected and processed as described in Section “Materials and Methods.” Bacterial concentrations were quantified in lungs (A) and in blood (B). Graphs depict means + SEM and p-values are indicated in the graphs.