Table 2.

Serum cytokine levels in AAT^+/+ and C57Bl/6 control mice^*.

	Infected with P.aer			Uninfected
Cytokine	AAT+/+ (N = 6)	C57Bl/6 (N = 4)	Percent reduction in infected AAT+/+ mice§	AAT+/+ (N = 5)	C57Bl/6 (N = 5)
IL-1α	11 ± 6.4	782 ± 668	98.6†	17 ± 10	65 ± 25
IL-1β	509 ± 177	4797 ± 2214	89.4†	0 ± 0	251 ± 138
IL-2	117 ± 50	586 ± 105	80.0‡	3.4 ± 3.4	10 ± 6.6
IL-3	149 ± 11	1226 ± 813	87.8‡	110 ± 13	92 ± 32
IL-4	88 ± 9.6	101 ± 27	12.9	110 ± 13	92 ± 32
IL-5	140 ± 89	2556 ± 344	94.5†	0 ± 0	0 ± 0
IL-6	2391 ± 733	12378 ± 2324	80.7†	11 ± 7.3	2.2 ± 1.7
IL-10	163 ± 46	529 ± 120	69.2‡	16 ± 7.8	11 ± 8.0
IL-12	171 ± 32	261 ± 110	34.5	17 ± 17	54 ± 28
IL-17	75 ± 11	1177 ± 607	93.6	14 ± 8.0	23 ± 13
MCP-1	464 ± 110	6920 ± 2655	93.3†	0 ± 0	0 ± 0
IFNγ	71 ± 7.7	1175 ± 583	94.0	30 ± 6.6	29 ± 6.2
TNFα	33 ± 6.2	400 ± 244	91.7	18 ± 6.5	18 ± 6.0
MIP-1α	157 ± 86	4812 ± 3088	96.7	17 ± 17	25 ± 13
GMCSF	115 ± 11	1321 ± 585	91.3†	41 ± 22	47 ± 32
RANTES	356 ± 81	3319 ± 1375	89.3	48 ± 6.4	61 ± 13

*Data expressed as means ± SEM pg/mL.

^§Percent reduction in AAT^+/+ mice compared to C57Bl/6 control mice 24 h following infection.

^†p = 0.01, ^‡p = 0.02.