. 2013 Dec 5;7(12):e2588. doi: 10.1371/journal.pntd.0002588

Table 3. RNA transcription profile of A. suum egg infected animals and L3 and L4 infected animals.

Gene	Description	Egg infection			L3 transfer			L4 transfer
		10 DPI	17 DPI	28 DPI	2 DPT	7 DPT	18 DPT	2 DPT	7 DPT	18 DPT
	Th1 associated
il12a	Interleukin 12 subunit p35	2.29^**	1.28	1.48	1.15	1.98	1.17	1.45	0.84	0.56
il12b	Interleukin 12 subunit p40	2.28^*	2.63	2.12^*	2.05^*	2.11^**	1.98	1.26	1.09	1.26
nos2a	Nitric oxide synthase 2a, inducible	2.11	5.12^*	8.81^**	1.19	1.24	0.97	2.41	1.35	1.43
ifng	Interferon γ	4.30^**	2.91^*	3.49^*	1.31	2.27	1.02	2.65^*	1.44	1.03
tbx21	T-Box 21, T-bet	2.28^*	1.63	2.05	2.35^*	1.59	1.83	1.37	1.04	1.06
stat4	Signal transducer and activator of transcription 4	1.66^*	0.96	1.70^*	1.31	1.15	1.33	6.49^*	3.84^*	3.42^*
	Th2 associated
il4	Interleukin 4	1.59	0.76	1.16	1.24^*	0.91	0.92	1.04	0.93	1.35
il5	Interleukin 5	1.06	0.92	0.84	0.79	0.91	0.80	0.78	0.59^*	0.53^*
il13	Interleukin 13	0.52	1.19	1.32	3.36	1.50^*	1.60^*	1.38	2.66	40.25^**
stat6	Signal transducer and activator of transcription 6	0.74	0.77	0.86	0.69	1.39	0.89	0.76	0.74	0.81
il25	Interleukin 25	1.36	1.20	1.95	1.27	0.83	0.89	0.41^*	0.92	1.59
il33	Interleukin 33	1.24	1.07	1.05	0.73	0.50	0.54	0.69	0.71	1.11
cma1	Mast cell chymase 1	0.87	0.68	0.94	0.80	0.54^*	1.04	0.89	0.68	0.68^*
	Treg
foxp3	Forkhead box P3	0.89	0.98	1.47	1.55	1.64^*	1.95^*	1.54	2.10	2.05^*
tgfb	transforming growth factor β	0.99	0.99	1.15	1.33	1.89^*	1.32	1.76^**	1.92	1.04
il10	Interleukin 10	1.13	1.74	1.33	0.84	1.25	0.59^**	1.84	1.65	1.33
pparg	peroxisome proliferator-activated receptor gamma	0.42^*	0.81	1.35	2.60^*	0.83	1.11	0.74	0.89	1.53
	Cytotoxic cell associated
nkl	NK-lysin	0.52	1.57	1.16	0.54	0.71	0.92	1.97	1.90	0.97
gzma	Granzyme A	1.61^**	1.46	2.74^**	2.03	2.05^*	2.25	1.59^*	1.46	0.24^**
gzmb	Granzyme B	4.14^*	2.66	3.69	2.58^**	1.32	2.34	3.74^**	2.11^*	1.04
prf1	Perforin 1	1.50	0.83	1.61	1.67^*	1.68^**	1.70^*	2.61^*	1.86	1.37
klrk	killer cell lectin-like receptor subfamily K, NKG2D	2.71^**	1.11	2.28^*	1.25	1.02	1.42	0.73	0.41	0.44^*
	Eosinophil associated
epx	Eosinophil peroxidase	2.64^*	0.33	0.41^*	0.48	0.44	0.68	0.43	0.73	3.47^**
ccl11	Chemokine (C-C motif) ligand 11, Eotaxin 1	1.03	0.79	0.98	1.25	2.17^*	1.38	0.88	0.79	0.87
ccr3	Eotaxin receptor	2.28^*	1.32	0.79	0.86	0.83	1.06	0.82	0.88	0.94
il5ra	Interleukin 5 Receptor, alpha	1.21	0.59	1.09	1.72	1.19	2.67^*	1.42	1.32	1.33

Results are shown as average fold change versus uninfected controls.

p<0.05 compared to uninfected controls.

^**

p<0.01 compared to uninfected controls.