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Figure 3.

Figure 3

CETP expression protects female mice against diet-induced insulin resistance. (A) Hyperinsulinemic-euglycemic clamp study design. (B) Clamp blood glucose in HFD-fed males. (C) Glucose infusion rate (GIR) required to maintain euglycemia during hyperinsulinemic clamp in HFD-fed males. (D) Insulin sensitivity index based on steady-state GIR/insulin for HFD-fed males. (E) Clamp blood glucose in HFD-fed females. (F) GIR for HFD-fed females. (G) Insulin sensitivity index for HFD-fed females. (H) Blood glucose during clamp in chow-fed females. (I) GIR for chow-fed females. (J) Insulin sensitivity index for chow-fed females. Data represent the mean±SEM from n=6–8 animals per group, *p<0.05.