Figure 5. GCs attenuate CM-induced neutrophil survival.
(A) The percentage of neutrophil survival when cultured in inflammatory CM at 21% oxygen levels, with or without dexamethasone (100 nM). (B) The percentage of neutrophil survival cultured in inflammatory CM at 1% oxygen levels, with or without dexamethasone (100 nM); 24 h (closed bars), 48 h (open bars), 72 h (cross-hatched bars), and 96 h (dotted bars). (C) The direct impact of the 1-ng/ml LPS on neutrophil survival in standard media at 21% oxygen levels after 24 h. Data represent n = 6 and are shown as mean ± sem. *P < 0.05; ***P < 0.001. Control, Noninflammatory CM.