Table 2. Alu-IR-mediated fragility in TET-POL3 and TET-POL2 mutants is Rad51-dependent.
Genetic background | GCR rate (×10−6) | Fold increase over wild-type |
WT | 41 (30–52)a | 1 |
Δrad51 | 37 (27–50) | 1 |
TET-POL3 | 460 (390–640) | 11 |
TET-POL3Δrad51 | 88 (58–108) | 2 |
TET-POL2 | 240 (210–270) | 6 |
TET-POL2Δrad51 | 63 (46–79) | 1 |
Numbers in brackets are the 95% confidence interval.