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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Curr Opin Microbiol. 2013 Oct 10;16(6):10.1016/j.mib.2013.09.006. doi: 10.1016/j.mib.2013.09.006

Figure 1. C. albicans mechanisms for acquiring iron and zinc from the host.

Figure 1

C. albicans has evolved systems targeting host hemoglobin, host transferrin, host ferritin, and siderophores as sources of iron, and the Pra1/Zrt1 system for scavenging zinc. The depicted transferrin receptor (“X”) is hypothetical (hyp.) The depicted variants of the hemoglobin receptor, iron reductase, multicopper ferroxidase, and iron permease are members of larger gene families with demonstrated in vitro activity.