Table 5. Logistic regression analysis of circulating miRNA levels in PCR validation cohort.

	UA versus SA			UA versus Control
MiRNAID	OR	95% CI	P	OR	95% CI	P
miR-106b	7.024	(2.728,18.082)	<0.001	2.389	(1.158, 4.927)	0.018
miR-25	7.367	(2.713,20.004)	<0.001	2.036	(1.048, 3.955)	0.036
miR-92a	10.170	(3.437,30.094)	<0.001	2.611	(1.110, 6.144)	0.028
miR-21	8.828	(3.302,23.603)	<0.001	2.488	(1.173, 5.277)	0.017
miR-590-5p	6.314	(2.534,15.729)	<0.001	2.678	(1.226, 5.849)	0.013
miR-126*	3.457	(1.730,6.910)	<0.001	1.882	(1.140, 3.108)	0.013
miR-451	6.664	(2.774,16.010)	<0.001	4.609	(2.171, 9.782)	<0.001

Logistic regression analysis comparing circulating miRNA levels between controls (n = 37), SA patients (n = 31), and UA patients (n = 45). Levels of the 7 selected circulating miRNAs were independently associated with UA after adjustment for age, sex, hypertension, dyslipidemia, diabetes mellitus, smoking status, and the use of statins and anti-platelet drugs. OR, odds ratio; 95% CI, 95% confidence interval.