Figure 5. Chemokine levels and macrophages infiltration into DEN-induced HCC.
A. Histological sections of WT and CHOP KO livers were stained for the macrophage marker F4/80. Total number of F4/80 positive cells (red arrows) were counted in seven different tumor zones in each sample (n = 5 of both genotypes, p<0.05). B. Analysis of mRNA expression of chemokines in tumor and parenchyma of WT and CHOP−/− mice.