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. 2013 Dec 5;8(12):e81054. doi: 10.1371/journal.pone.0081054

Table 4. Features of studied subjects according to the tertiles of urinary sodium excretion and p22-phox C242T genotypes.

Characteristics Low (<67 mEq/12 h) Medium (67–111 mEq/12 h) High (>111 mEq/12 h)
p22-phox(C242T) Genotype CC CT+TT CC CT+TT CC CT+TT
N (%) 184 (43) 247 (57) 178 (42) 248 (58) 194 (44) 247 (56)
Clinical
Age, years 41.7±0.7 43.1±0.7 43.9±0.8 42.7±0.6 44.8±0.8 43.9±0.7
Gender (Male/Female) 75/109 93/152 97/81 97/153 113/81 154/93
Systolic blood pressure, mmHg 121.9±1.5 121.5±1.3 124.7±1.4 121.2±1.0 125.5±1.2 129.1±1.3*
Diastolic blood pressure, mmHg 80.4±1.0 79.1±0.8 82.0±0.9 80.6±0.7 83.9±0.9 86.9±0.9*
Body mass index, kg/m2 25.1±0.4 25.2±0.3 25.7±0.3 24.9±0.3 26.2±0.3 27.1±0.3
Smoking, n (%) 48 (26) 51 (21) 43 (24) 51 (20) 44 (23) 69 (28)
Hypertension, n (%) 53 (29) 65 (26) 61 (34) 73 (29) 80 (41) 124 (50)
Diabetes mellitus, n (%) 33 (18) 34 (14) 23 (13) 41 (16) 28 (14) 54 (22)
Race (Caucasian-descent), n (%) 84 (46) 105 (43) 67 (38) 108 (43) 85 (44) 89 (36)
Serum analysis
Glycemia, mg/dL 100.6±2.2 99.5±1.2 100.9±1.8 101.9±1.7 102.4±2.1 104.8±2.0
Uric acid, mg/dL 4.5±0.1 4.7±0.1 4.7±0.1 4.4±0.1 5.2±0.4 5.0±0.1
Creatinine, mg/dL 0.97±0.16 0.93±0.01 0.96±0.01 0.94±0.01 0.98±0.01 1.00±0.01
Triglycerides, mg/dL 123.6±7.1 113.8±5.0 123.1±6.7 120.6±5.7 139.6±7.1 148.0±7.1
HDL-cholesterol, mg/dL 54.7±2.8 50.1±1.8 49.6±2.1 49.4±1.7 52.6±3.1 50.7±2.2
LDL-cholesterol, mg/dL 138.2±2.9 141.5±2.5 138.5±3.2 140.1±2.5 140.2±2.9 137.4±2.3
12 h urinary analysis
Sodium, mEq 43.4±1.1 44.6±0.9 85.7±0.9 87.7±0.8 156.7±3.2 161.5±3.3
Potassium, mEq 16.2±0.7 16.6±0.7 20.5±0.8 22.0±0.8 32.3±1.5 29.6±0.9

Legend. HDL – high-density-lipoprotein; LDL – low-density-lipoprotein;

*

p<0.05 in comparison with CC genotype.